SELECTED PUBLICATIONS

2007 (links)

Ling, J., Roy, H. and Ibba, M. (2007)
Mechanism of tRNA-dependent editing in translational quality control.
Proc. Natl. Acad. Sci. USA 104, 72-77.

Prætorius-Ibba, M., Hausmann, C., Paras, M., Rogers, T.E. and Ibba, M. (2007)
Functional association between three archaeal aminoacyl-tRNA synthetases.
J. Biol. Chem. 282, 3680-3687.

Hausmann, C.D., Ling, J. and Ibba, M. (2007)
The unnatural culture of amino acids.
Nature Methods 4, 205-206.

Godinic, V., Mocibob, M., Rocak, S., Ibba, M. and Weygand-Durasevic, I. (2007)
Peroxin Pex21p interacts with C-terminal noncatalytic domain of yeast seryl-tRNA synthetase and forms a specific ternary complex with tRNASer.
FEBS Journal 274, 2788-2799.

Levengood, J., Roy, H., Ishitani, R., Söll, D., Nureki, O., and Ibba, M. (2007)
Anticodon recognition and discrimination by the a-helix cage domain of class I lysyl-tRNA synthetase.
Biochemistry 46, 11033-11038.

Ling, J., Roy, H., Qin, D., Rubio, M.A., Alfonzo, J.D., Fredrick, K. and Ibba, M. (2007)
Pathogenic mechanism of a human mitochondrial tRNAPhe mutation associated with MERRF syndrome.
Proc. Natl. Acad. Sci. USA 104, 15299-15304.

Hausmann, C.D., Prætorius-Ibba, M. and Ibba, M. (2007)
An aminoacyl-tRNA synthetase:elongation factor complex for substrate channeling in archaeal translation.
Nucleic Acids Res. 35, 6094-6102.

Ling, J., Yadavalli, S. and Ibba, M. (2007)
Phenylalanyl-tRNA synthetase editing defects result in efficient mistranslation of phenylalanine codons as tyrosine.
RNA 13, 1881-1886.

Ataide, S.F., Wilson, S.N., Dang, S., Rogers, T.E., Roy, B., Banerjee, R., Henkin, T.M. and Ibba, M. (2007)
Mechanisms of resistance to an amino acid antibiotic that targets translation.
ACS Chemical Biology 2, 819-827.
 

2006 (links)

Roy, H. and Ibba, M . (2006)

Sticky end in protein synthesis.

Nature 443 , 41-42.

Ataide, S.A. and Ibba, M. (2006)

Small molecules - big players in the evolution of protein synthesis.

ACS Chemical Biology 1, 285-297.

Roy, H. and Ibba, M. (2006)

Phenylalanyl-tRNA synthetase contains a dispensable RNA binding domain that contributes to editing of non-cognate aminoacyl-tRNA.

Biochemistry 45, 9156-9162.

Metlitskaya, A., Kazakov, T., Kommer, A., Pavlova, O., Prætorius-Ibba, M., Ibba, M. Krasheninnikov, I., Kolb, V., Khmel, I. and Severinov, K. (2006)

Aspartyl-tRNA synthetase is the target of peptidenucleotide antibiotic Microcin C.

J. Biol. Chem. 281, 18033 - 18042.

Prætorius-Ibba, M., Ataide, S., Hausmann, C., Levengood, J., Ling, J., Wang, S., Roy, H. and Ibba, M. (2006)

Quality Control during aminoacyl-tRNA synthesis.

Chemistry in Industry 55, 129-134.

Wang, S., Prætorius-Ibba, M., Ataide, S., Roy, H. and Ibba, M. (2006)

Discrimination of cognate and non-cognate substrates at the active site of class I lysyl-tRNA synthetase.

Biochemistry 45, 3646-3652.

Rubio, M.A.T., Ragone, F.L., Gaston, K.W., Ibba, M. and Alfonzo, J.D. (2006)

C to U editing stimulates A to I editing in the anticodon loop of a cytoplasmic threonyl tRNA in Trypanosoma brucei.

J. Biol. Chem., 281, 115-120.

2005 (links)

Roy, H., Ling, J., Alfonzo, J.D. and Ibba, M. (2005)

Loss of editing activity during the evolution of mitochondrial phenylalanyl-tRNA synthetase.

J. Biol. Chem. 280, 38186-38192.

Ataide, S.F., Jester, B.C., Devine, K.M. and Ibba, M. (2005)

Stationary phase expression and aminoacylation of a tRNA-like small RNA.

EMBO Reports 6,742-746.

Prætorius-Ibba, M., Rogers, T.E., Samson, R., Kelman, Z. and Ibba, M. (2005)

Association between archaeal prolyl-and leucyl-tRNA synthetases enhances tRNAPro aminoacylation.

J. Biol. Chem. 280, 26099-26104.

Ibba, M., Francklyn, C., and Cusack, S., eds. (2005)

The Aminoacyl-tRNA synthetases. Landes Bioscience, Georgetown, Texas.

Ambrogelly, A., Frugier, M., Ibba, M., Söll, D., Giegé, R. (2005)
Transfer RNA recognition by class I lysyl-tRNA synthetase from the Lyme disease pathogen Borrelia burgdorferi.
FEBS Lett. 579, 2629-2634.

Sauerwald, A., Zhu, W., Major, T.A., Roy, H., Palioura, S., Jahn, D., Whitman, W.B., Yates, J.R. 3rd, Ibba, M . and Söll,D. (2005)

RNA-dependent cysteine biosynthesis in archaea.

Science 307, 1969-1972.

2004 (links)

Roy, H., Ling, J., Irnov, and Ibba, M. (2004)

Post-transfer editing in vitro and in vivo by the beta-subunit of phenylalanyl-tRNA synthetase.

EMBO J. 23, 4639-4648

Ataide, S.F. and Ibba, M. (2004)

Discrimination of cognate and non-cognate substrates at the active site of class II lysyl-tRNA synthetase.

Biochemistry 43, 11836-11841.

Ibba, M., and Francklyn, C. (2004)

Turning tRNA upside down: when aminoacylation is not a prerequisite to protein synthesis.

Proc. Natl. Acad. Sci. USA 101, 7493-7494.

Korencic, D., Ahel, I., Schelert, J., Sacher, M., Ruan, B., Stathopoulos, C., Blum, P., Ibba, M., and Söll,D. (2004)

A freestanding proofreading domain is required for protein synthesis quality control in Archaea.

Proc. Natl. Acad. Sci. USA 101, 10260-10265.

Bentin, T., Hamzavi, R., Salomonsson, J., Roy, H., Ibba, M ., and Nielsen, P.E. (2004)

Photoreactive bicyclic amino acids as substrates for mutant Escherichia coli phenylalanyl-tRNA synthetases.

J. Biol. Chem. 279, 19839-19845.

Levengood, J.D., Ataide, S.F., Roy, H., and Ibba, M. (2004)

Divergence in non-cognate amino acid recognition between class I and class II lysyl-tRNA synthetases.

J. Biol. Chem. 279, 17707-17714.

Ibba, M. and Söll, D. (2004)

Aminoacyl-tRNAs: Setting the limits of the genetic code.

Genes Dev. 18, 731-738.

2003 (links)

Jester, B., Levengood, J., Roy, H., Ibba, M., and Devine, K. (2003)

Non-orthologous replacement of lysyl-tRNA synthetase prevents addition of lysine analogs to the genetic code.

Proc. Natl. Acad. Sci. USA 100, 14351-14356.

Polycarpo, C., Ambrogelly, A., Ruan, B., Tumbula-Hansen, D., Ataide, S.F., Ishitani, R.,

Yokoyama, S., Nureki, O., Ibba, M., and Söll, D. (2003)

Activation of the pyrrolysine suppressor tRNA requires formation of a ternary complex with class I

and class II lysyl-tRNA synthetases. Mol. Cell 12, 287-294.

Mejlhede, N., Monthan, A., Theisen, M. and Ibba, M. (2003)

Differentiation of Borrelia burgdorferi sensu lato strains using class I lysyl-tRNA synthetase encoding genes.

Med Microbiol. Immunol. 192, 79-83.

Prætorius-Ibba, M. and Ibba, M. (2003)

Aminoacyl-tRNA synthesis in archaea: different but not unique.

Mol. Microbiol. 48, 631-637.

2002 (links)

Ambrogelly, A., Korencic, D. and Ibba, M. (2002)

Functional annotation of class I lysyl-tRNA synthetase phylogeny indicates a limited role for gene transfer.

J. Bacteriol. 184, 4594-4600.

Pavlickova, P., Jensen, N.M., Paul, H., Schaeferling, M., Giammasi, C., Kruschina, M., Du, W.D., Theisen,

M., Ibba, M., Ortigao, F. and Kambhampati, D. (2002)

Antibody detection in human serum using a versatile protein chip platform constructed by applying

nanoscale self-assembled architectures on gold.

J. Proteome. Res. 1, 227-231.

Terada, T., Nureki, O., Ishitani, R., Ambrogelly, A., Ibba, M., Söll, D. and Yokoyama, S. (2002)

Functional convergence of two lysyl-tRNA synthetases with unrelated topologies.

Nature Struct. Biol. 9, 257-262.

2001 (links)

Ibba, M. (2001)

Discriminating right from wrong.

Science 294, 70-71.