Stephen T. Abedon

abedon.1@osu.edu

Ph.D., University of Arizona

Associate Professor, Department of Microbiology

Bacteriophage Ecology and Evolutionary Ecology

Bacteriophage, or phage, are the viruses of bacteria. I am interested especially in phage adaptation: how phages can and have optimized their characteristics toward meeting the challenges of growth and survival. My research consists of a combination of theoretical and empirical analyses of phage population growth and structure as it occurs within both broth and semi-solid environments. My overall goal is to develop a more complete theoretical understanding of the constraints acting on phage evolution.

Abedon, S.T., Duffy, S., Turner, P. E. 2009. Bacteriophage Ecology. Encyclopedia of Microbiology. Schaechter, M. (ed), Elsevier, Oxford, pp. 42-57.

Hyman, P., Abedon, S.T. 2009. Bacteriophage (Overview). Encyclopedia of Microbiology. Schaechter, M. (ed). Elsevier, Oxford, pp. 322-338.

Abedon, S. T. 2009. Phage Evolution and Ecology. Advances in Applied Microbiology 67:1-45.

Hyman, P., Abedon, S.T. 2009. Practical Methods for Determining Phage Growth Parameters. Methods in Molecular Biology 501:175-202.

Abedon, S.T., Yin, J. 2009. Bacteriophage Plaques: Theory and Analysis. Methods in Molecular Biology 501:161-174.

Abedon, S. T. (ed.) 2008. Bacteriophage Ecology: Population Growth, Evolution, and Impact of Bacterial Viruses. Cambridge University Press.

Goodridge, L., Abedon, S. T. 2008. Bacteriophage-Mediated Biocontrol of Bacterial Pathogens: Applications and Recent Regulatory Developments in the United States. Microbiology Australia 29(March):48-49.

Abedon, S.T. 2008. Ecology of Viruses Infecting Bacteria. In: Encyclopedia of Virology, Mahy, B., van Regenmortel, M. (eds). Elsevier, Oxford, pp. 71-77.

Abedon, S.T., Breitenberger, C., Williams, J., Roden, E. 2008. Ecological Processes: Respiration. Encyclopedia of Ecology. Jørgensen, S. E., Fath, B. D. (eds). Elsevier, Oxford, pp. 3010-3020.

Abedon, S.T., Culler, R.R. 2007. Optimizing Bacteriophage Plaque Fecundity. Journal of Theoretical Biology 249:582-592.

Dennehy, J., Abedon, S. T., Turner, P. E.* 2007. Host Density Impacts Relative Fitness of Bacteriophage φ6 Genotypes in Structured Habitats. Evolution 61:2516-2527.

Abedon, S.T., Culler, R.R. 2007. Bacteriophage Evolution Given Spatial Constraint. Journal of Theoretical Biology 248:111-119.

Calendar, R. (ed.) and Abedon, S. T. 2006. The Bacteriophages, 2nd edition. Oxford University Press.

Abedon, S.T. and LeJeune, J.T. 2005. Why Bacteriophage Encode Toxins and other Virulence Factors. Evolutionary Bioinformatics 1:97-110.

LeJeune, J.T., Abedon, S.T., Takemura, K., Christie, N.P. Sreevatsan, S. 2004. Human Escherichia coli O157:H7 Genetic Marker in Isolates of Bovine Origin. Emerging Infectious Diseases 10(8):1482-1485.

Abedon, S. T., Hyman, P., Thomas, C. 2003. Experimental Examination of Latent-Period Evolution as a Response to Bacterial Availability. Applied and Environmental Microbiology 69:7499-7506.

Goodridge, L., Abedon, S. T. 2003. Bacteriophage Biocontrol and Bioprocessing: Application of Phage Therapy to Industry. SIM News (Society for Industrial Microbiology News) 53(6):254-262.

Gill, J., Abedon, S. T. 2003. Bacteriophage Ecology and Plants. APSnet Feature, November 2003.