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Stephen T. Abedon

Stephen T. Abedon

abedon.1@osu.edu

Associate Professor.
Ph.D., University of Arizona, 1990

 

Bacteriophage Ecology and Evolutionary Ecology

Bacteriophage, or phage, are the viruses of bacteria. I am interested especially in phage adaptation: how phages can and have optimized their characteristics toward meeting the challenges of growth and survival. My research consists of a combination of theoretical and empirical analyses of phage population growth and structure as it occurs within both broth and semi-solid environments. My overall goal is to develop a more complete theoretical understanding of the constraints acting on phage evolution.

Recent Publications

Edited Volumes

Abedon, S.T. (2008). Bacteriophage Ecology: Population Growth, Evolution, and Impact of Bacterial Viruses. Cambridge University Press: Cambridge, UK.

Calendar, R. & Abedon, S.T. (2006). The Bacteriophages Edition 2. Oxford University Press: Oxford, UK.

Phage Articles & Chapters

Goodridge, L. & Abedon, S.T. (2008). Bacteriophage biocontrol- the technology matures. Microbiology Australia 29(March):48-49.

Abedon, S.T. & Culler, R.R. (2007). Optimizing bacteriophage plaque fecundity. Journal of Theoretical Biology 249:582-592.

Dennehy, J.J., Abedon, S.T. & Turner, P.E. (2007). Host density impacts relative fitness of bacteriophage Phi-6 genotypes in structured habitats. Evolution 61:2516-2527.

Abedon, S.T. & Culler, R.R. (2007). Bacteriophage Evolution Given Spatial Constraint. Journal of Theoretical Biology 248:111-119.

Abedon, S.T. (2006). Phage Ecology. In R. Calendar & S.T. Abedon (eds): The Bacteriophages Edition 2. Oxford University Press, pp. 37-46.

Abedon, S.T. & LeJeune, J.T. (2005). Why Bacteriophage Encode Exotoxins and Other Virulence Factors. Evolutionary Bioinformatics 1:97-110. Click for PDF

Breitbart, M., Rohwer, F. & Abedon, S.T. (2005). Phage Ecology and Bacterial Pathogenesis. In M.K. Waldor, D.I. Friedman & S.L. Adhya (eds): Phages: Their Role in Bacterial Pathogenesis and Biotechnology, ASM Press: Washington, DC. pp. 66-91.

LeJeune J.T, Abedon, S.T., Takemura, K., Christie, N.P. & Sreevatsan, S. (2004). Human Escherichia coli O157:H7 genetic marker in isolates of bovine origin. Emerging Infectious Diseases 10:1482-1485. Click for PDF

Goodridge, L. & Abedon, S.T. (2003). Bacteriophage Biocontrol and Bioprocessing: Application of Phage Therapy to Industry. SIM News, 53:254-262. Click for PDF

Abedon, S.T. , Hyman, P. & Thomas, C. (2003). Bacteriophage Latent-Period Evolution as a Response to Bacteria Availability: An Experimental Examination. Applied and Environmental Microbiology, 69:7499-7506. Click for PDF

Gill, J.J. & Abedon, S.T. (2003). Bacteriophage Ecology and Plants. APSnet Feature , November 2003, http://www.apsnet.org/online/feature/phages/ . Click for PDF

Abedon, S.T. , Herchler, T. D., & Stopar, D. (2001). Bacteriophage latent-period evolution as a response to resource availability. Applied and Environmental Microbiology 67:4233-4241. Click for PDF

Abedon, S.T. (2000). The murky origin of Snow White and her T-even Dwarfs. Genetics 155:481-486. Click for PDF

Abedon, S.T. (1999). Bacteriophage T4 resistance to lysis-inhibition collapse. Genetical Research 74:1-11. Click for PDF

Paddison, P., Abedon, S.T. , Dressman, H., Gailbreath, K., Tracy, J., Mosser, E., Neitzel, J., Guttman, B., & Kutter, E. (1998). Lysis inhibition and fine-structure genetics in bacteriophage T4. Genetics 148:1539-1550. Click for PDF

Abedon, S.T. (1994). Lysis and the interaction between free phages and infected cells. The Molecular Biology of Bacteriophage T4. Jim D. Karam, John W. Drake, Kenneth N. Kreuzer, Gisela Mosig, Dwight Hall, Frederick A. Eiserling, Lindsay W. Black, Elizabeth Kutter, Karin Carlson, Eric S. Miller, and Eleanor Spicer (eds). Washington, DC: ASM Press. pp. 397-405. Click for PDF

Abedon, S.T. (1992). Lysis of lysis-inhibited bacteriophage T4 infected cells. Journal of Bacteriology 174:8073-8080. Click for PDF

Abedon, S.T. (1990). Selection for lysis inhibition in bacteriophage. Journal of Theoretical Biology 146:501-511. Click for PDF

Abedon, S.T. (1989). Selection for bacteriophage latent period length by bacterial density: A theoretical examination. Microbial Ecology 18:79-88. Click for PDF

Abedon, S.T. (1990). The Ecology of Bacteriophage T4. Ph.D. Dissertation, University of Arizona. Click for PDF

Stephen T. Abedon Home Page , Phage Ecology , The Bacteriophages

Department of Microbiology; The Ohio State University; 376 Bioscience Building; 484 West 12th Ave.; Columbus, Ohio USA; 43210-1292; Phone: 614-292-2301; Fax: 614-292-8120
Riffe Research Center

 

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Department of Microbiology
The Ohio State University
376 Biological Sciences Building
484 West 12th Ave.
Columbus, Ohio USA 43210-1292
Phone: 614-292-2301
Fax: 614-292-8120

The Ohio State University

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