Professor, Microbiology; Molecular Virology, Immunology and
Medical Genetics
Research
Summary:
Herpesvirus replication; dUTPase as a target site
for the development of anti-viral and anti-cancer
drugs; Mechanisms of heavy metal mutagenesis; Mutagenesis
and DNA repair in carcinogenesis; Mycoplasma evolution.
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Bijur, G.N., Briggs, B., Hitchcock, C.L. and Williams,
M.V. 1999. Ascorbic acid-dehydroascorbate induces
arrest at the G2/M checkpoint during oxidative
stress. Environmental and Molecular Mutagenesis
33:144-152.
Ariza, M.E. and Williams, M.V. 1999. Lead and
mercury mutagenesis: Type of mutation dependent
upon metal concentration. J. Biochem. Molecular
Toxicology 13:107-112.
Williams, M.V., Studebaker A.W and Balendiran
G.K. 1999. Subunit arrangement and substrate specificity
of homotrimeric dUTPases. J. Mol. Biol. Biotechnol.
1:23-34.
Ariza, M.E., Bijur, G.E. and Williams,
M.V. (1999).
Environmental Metal Pollutants, Reactive Oxygen
Intermediates and Genotoxicity. Kluwer Academic
Publishers. |
