Day J, Friedman A, Schlesinger LS. Modeling the immune rheostat of macrophages in the lung in response to infection. PNAS. Epub ahead of print.
Wang S-H, Pancholi P, Stevenson K, Yakrus MA, Butler WR, Schlesinger LS, Mangino JE. Pseudo-outbreak of “Mycobacterium paraffinicum” in a tertiary care medical center. In press, Infection Control and Hospital Epidemiology.
Sow FB, Alvarez GR, Gross RP, Satoskar AS, Schlesinger LS, Zwilling BS, Lafuse WP. Role of STAT1, NF-κB, and C/EBPβ in the macrophage transcriptional regulation of hepcidin by mycobacterial infection and IFN-γ (in press, J. Leuko. Bio.).
Lustberg M, Schlesinger LS, Mangino J. 2009. Concerns regarding “Complicated Skin and Skin-Structure Infections and Catheter-Related Bloodstream Infections: Noninferiority of Linezolid in a Phase 3 Study.” Letter to the editor. Clin Infect Dis. 49:313-314.
Torrelles JB, DesJardin LE, MacNeil J, Kaufman TM, Kutzbach B, Knaup R, McCarthy TR, Gurcha SS, Besra GS, Clegg S, Schlesinger LS. 2009. Inactivation of Mycobacterium tuberculosis mannosyltransferase pimB reduces cell wall lipoarabinomannan and lipomannan content and increases the rate of bacterial-induced human macrophage cell death. Glycobiology 19:743-755.
Premanandan C, Storozuk C, Clay C, Lairmore MD, Schlesinger LS, Phipps AJ. 2009. Complement protein C3 binding to Bacillus anthracis spores enhances phagocytosis by human macrophages. Micro. Pathog. 46:306-314.
Chiu H-C, Yang J, Soni S, Kulp SK, Gunn JS, Schlesinger LS, Chen C-S. 2009. Pharmacological exploitation of an off-target antibacterial effect of the cyclooxygenase-2 inhibitor Celecoxib against Francisella tularensis. Antimicrob Agents and Chemotherapy 53:2998-3002.
Torrelles JB, Azad AK, Henning LH, Carlson TK, Schlesinger LS. 2008. Role of C-type lectins in mycobacterial infections. Current Drug Targets 9:102-112.
Ernst JD, Lewinsohn DM, Behar S, Blythe M, Schlesinger LS, Kornfeld H, and Sette A. 2008. Meeting Report: NIH Workshop on the Tuberculosis Immune Epitope Database. Tuberculosis.
Wang S-H, Mangino, JE, Stevenson K, Yakrus MA, Cooksey R, Butler WR, Healy M, Wise MG, Schlesinger LS, Pancholi P. 2008. Characterization of “Mycobacterium paraffinicum” associated with a pseudo-outbreak. J. Clin. Micro. 46:1850-1853.
Parsa KVL, Butchar JP, Rajaram MVS, Cremer TJ, Gunn JS, Schlesinger LS, Tridandapani S. 2008. Francisella gains a survival advantage within macrophages by suppressing the host IFNγ response. Mol. Immunol. 45:3428-3437.
Henning LN, Azad AK, Parsa KVL, Crowther JE, Tridandapani S, Schlesinger LS. 2008. Pulmonary Surfactant Protein-A: A key regulator of Toll-Like Receptor expression and activity in human macrophages. J. Immunol. 180:7847-7858.
Van Zandt KE, Sow FB, Florence WC, Zwilling BS, Satoskar AR, Schlesinger LS, Lafuse WP. 2008. The iron export protein Ferroportin 1 is differentially expressed in mouse macrophage populations and is present in the mycobacterial-containing phagosome. J. Leuko. Bio. 84:689-700.
Butchar JP, Cremer TJ, Clay CD, Gavrilin MA, Wewers MD, Marsh CB, Schlesinger LS, Tridandapani S. 2008. Microarray analysis of human monocytes infected with Francisella tularensis identifies new targets of host response subversion. PLoS ONE 3:e2924:1-8.
Clay CD, Soni S, Gunn JS, Schlesinger LS. 2008. Evasion of complement-mediated lysis and complement C3 deposition are dictated by Francisella tularensis LPS O-antigen J. Immunol. 181:5568-5578.
Azad AK, Torrelles JB, Schlesinger LS. Mutation in the DC-SIGN cytoplasmic triacidic cluster motif markedly attenuates receptor activity for both phagocytosis and endocytosis of mannose-containing ligands by human myeloid cells. J. Leuko. Bio. 84:1594-1603.
Torrelles JB, Knaup R, Kolareth A, Slepushkina T, Kaufman TM, Kang P, Hill PJ, Brennan PJ, Chatterjee D, Belisle JT, Musser JM, Schlesinger LS. 2008. Identification of Mycobacterium tuberculosis clinical isolates with altered phagocytosis by human macrophages due to a truncated lipoarabinomannan. J Biol Chem. 283:31417-31428.
Olakanmi O, Schlesinger LS, and Britigan BE. Hereditary hemochromatosis results in decreased iron acquisition and growth by Mycobacterium tuberculosis within human macrophages. J Leuko Bio 81:195-204, 2007.
Mohaptra NP, Balagopal A, Soni S, Schlesinger LS, Gunn JS. 2007. AcpA is a Francisella Acid Phosphatase that affects Intramacrophage Survival and Virulence. Infect. Immun. 75: 390-396.
Young JD, Balagopal A, Reddy NS, Schlesinger LS. 2007. Pulmonary infections caused by non-tuberculous mycobacteria: An update on epidemiology, diagnosis, and treatment. J. Resp. Dis 28: 7-18.
Butchar JP, Rajaram MVS, Ganesan LP, Parsa KVL, Clay CD, Schlesinger LS, Tridandapani S. 2007. Francisella tularensis induces Interleukin-23 production in human monocytes. J. Immunol. 178:4445-4454.
Torrelles JB, Azad AK, Schlesinger LS. 2006. Fine discrimination in the recognition of individual species of phosphatidyl-myo-inositol mannosides from Mycobacterium tuberculosis by C-type lectin pattern recognition receptors. J. Immunol. 177:1805-1816.
Parsa KVL, Ganesan LP, Rajaram MVS, Gavrilin MA, Wewers MD, Schlesinger LS, Gunn JS, Tridandapani S. 2006. Macrophage pro-inflammatory response to Francisella novicida infection is regulated by the SH2 domain-containing inositol 5’ phosphatase SHIP. PLOS Pathogens 2:0681-0690.
Balagopal A, MacFarlane AS, Mohapatra N, Soni S, Gunn JS, Schlesinger LS. 2006. Characterization of the receptor-ligand pathways important for entry and survival of Francisella tularensis in human macrophages. Infect. Immun. 74: 5114-5125.
Ferguson JS, Martin JL, Azad AK, McCarthy TR, Kang PB, Voelker DR, Crouch EC, and Schlesinger LS. 2006. Surfactant Protein D Increases fusion of Mycobacterium tuberculosis-containing phagosomes with lysosomes in human macrophages. Infect. Immun. 74:7005-7009.
Crowther
JE and Schlesinger LS.
2006. Defining the phagocytic pathway for Surfactant
Protein A in human macrophages: binding,
clathrin-dependent Uptake, and trafficking
through the endolysosomal pathway. Am J
Physiol. 290:L334-L342.
Beharka
AA, Crowther JE, McCormack FX, Denning G,
Lees J, Tibesar E, Schlesinger LS.
2005. Pulmonary Surfactant Protein A activates
a PI3 Kinase / calcium signal transduction
pathway in human macrophages: participation
in the up-regulation of mannose receptor
activity. J. Immunol. 175: 2227-2236.
Kang
PB, Azad AK, Torrelles JB, Kaufman TM, Beharka
A, Tibesar E, Schlesinger LS.
2005. The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated
phagosome biogenesis J Exp. Med. 202:987-999.
McCarthy
TR, Torrelles JB, MacFarlane A, Katawczik
M, Kutzbach B, Clegg S, DesJardin LE, Goldberg
JB, Schlesinger LS. 2005. Mycobacterium
tuberculosis manB, a phosphomannomutase
that increases phosphatidylinositol mannoside
biosynthesis in M. smegmatis and mycobacterial
association with Human Macrophages. Mol.
Micro. 58:774-790.
Olakanmi
O, Schlesinger LS, Ahmed
A, Britigan BE. 2004. The nature of extracellular
iron influences iron acquisition by Mycobacterium
tuberculosis residing within human macrophages.
Infect. Immun. 72:2022-2028.
Ferguson
JS, Weis JJ, Martin JL, Schlesinger
LS. 2004. Complement protein C3 binding
to Mycobacterium tuberculosis is initiated
by the classical pathway in human bronchoalveolar
lavage fluid. Infect. Immun. 72:2564-2573.
Crowther
JE, Kutala VK, Kuppusamy P, Ferguson JS,
Beharka AA, Zweier JL, McCormack FX, Schlesinger
LS. 2004. Pulmonary Surfactant Protein
A inhibits macrophage reactive intermediate
production in response to stimuli by reducing
NADPH oxidase activity. J. Immunol. 172:6866-6874.
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